Quiz Questions And Answers

Which results in perofrin cell membrane damage?

Fas-FasL binding

TNF receptor association with adapter protein TRADD

Cytotoxic T- Lympocyte Simulated apoptosis

Which molecule is a negative signal involved in induction of apoptosis?

IL-2

TNF

Bcl-2

Which domain is a apoptosis suppresser?

Caspase associated recruitment domains

BIR domains (IAPs)

Caspase (catalytic) domains

Which caspase does caspase 8 and 9 activate which then leads to a cascade?

Increased venous hydrostatic pressure would lead to a decrease in edema

True

False

The caspace cascade is an example of hwich stage of apoptosis?

Control Stage

Commitment

Execution stage

A bax heterodimer withBcl-2 or Bcl-XL will promote apoptosis

True

False

Prostate atrophy after castration, regression of lactating breast milk after weaning, and ovarian follicular atresia in menopuase are examples of

Necrosis

Apoptosis

Caspase (catalytic) domains

What is often the first step in signal transduction pathways leading to apoptosis?

Clustering of intracellular, frequently nuclear receptors

Glucocorticoid interaction with nuclear receptors

Viral entrance to the cell

Binding of _ ligand to _ receptor is involved in T-cell development or clonal deletion?

TNF to TNFR1

TRAIL to DR3

FasL to Fas

ANSWERS

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