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Pathobiology or pathology – the study of diseases Quiz

Pathobiology or pathology – the study of diseases Quiz

Pathobiology or pathology – the study of diseases Quiz Test

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Quiz Questions And Answers

Which results in perofrin cell membrane damage?

Fas-FasL binding
TNF receptor association with adapter protein TRADD
Cytotoxic T- Lympocyte Simulated apoptosis

Which molecule is a negative signal involved in induction of apoptosis?

IL-2
TNF
Bcl-2

Which domain is a apoptosis suppresser?

Caspase associated recruitment domains
BIR domains (IAPs)
Caspase (catalytic) domains

Which caspase does caspase 8 and 9 activate which then leads to a cascade?

12
3
7

Increased venous hydrostatic pressure would lead to a decrease in edema

True
False

The caspace cascade is an example of hwich stage of apoptosis?

Control Stage
Commitment
Execution stage

A bax heterodimer withBcl-2 or Bcl-XL will promote apoptosis

True
False

Prostate atrophy after castration, regression of lactating breast milk after weaning, and ovarian follicular atresia in menopuase are examples of

Necrosis
Apoptosis
Caspase (catalytic) domains

What is often the first step in signal transduction pathways leading to apoptosis?

Clustering of intracellular, frequently nuclear receptors
Glucocorticoid interaction with nuclear receptors
Viral entrance to the cell

Binding of _____ ligand to _____ receptor is involved in T-cell development or clonal deletion?

TNF to TNFR1
TRAIL to DR3
FasL to Fas
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